Wimbledon champion Petra Kvitova became the latest big-name casualty in the women's draw at the US Open with a shock third-round loss to qualifier Aleksandra Krunic.
Kvitova much prefers the quiet of Wimbledon to the hustle and bustle of New York and she has never been beyond the fourth round at Flushing Meadows.
Her first two performances had raised hopes that she could break her hoodoo this time, but she could not break down the stubborn Krunic and lost 6-4 6-4.
The 21-year-old Serbian, ranked 145th, had never won a grand slam match before this tournament, but followed up her upset of Madison Keys with an even bigger scalp.
Kvitova, who had her right thigh heavily strapped, looked to have turned things around when battled back from 4-2 down to 4-4 in the second set, but Krunic did an exceptional job at making the Czech hit one more ball.
Krunic also came up with some terrific shots of her own, showing remarkable composure for a player who had never taken a set off a top-30 player prior to this tournament.
When Kvitova sent her final forehand wide, the Serbian fell to the ground in celebration.
There are now only five of the top 10 women's seeds left in the tournament, with Kvitova joining Simona Halep, Agnieszka Radwanska, Angelique Kerber and Ana Ivanovic in falling early.